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10A) MEDICATION AND SUICIDE RISKS

24th Feb, 2021 | Information

https://www.bmj.com/content/350/bmj.h517

Conclusion: Rates of suicide and attempted suicide or self harm were similar during periods of treatment with selective serotonin reuptake inhibitors and tricyclic and related antidepressants. Mirtazapine, venlafaxine, and trazodone were associated with the highest rates of suicide and attempted suicide or self harm, but the number of suicide events was small leading to imprecise estimates. As this is an observational study the findings may reflect indication biases and residual confounding from severity of depression and differing characteristics of patients prescribed these drugs. The increased rates in the first 28 days of starting and stopping antidepressants emphasise the need for careful monitoring of patients during these periods.

SAFEGUARDING FOR MOTHERS AND BABIES WHERE PSYCHOTROPIC MEDICATION IS PRESCRIBED: For 4years I have complained about this, and it continues to be neglected.  

SAMANTHA FORD (19A) : THE INQUEST ON HER TWIN INFANTS, DETAILS: SHE WAS PRESCRIBED MIRTAZAPINE SHORTLY BEFORE SHE DROWNED THEM, 18 months after Rebecca’s suicide. See AntiDepaware

10B) MIRTAZAPINE
https://www.medicalnewstoday.com/articles/mirtazapine-oral-tablet
FDA warning: Suicide risk

  • This drug has a black box warning. This is the most serious warning from the Food and Drug Administration (FDA). A black box warning alerts doctors and patients about drug effects that may be dangerous.

https://www.ehealthme.com/ds/mirtazapine/completed-suicide/

From the numbers of reported side effects 67.71 % have completed suicide in the 1st month. 3.73% Mirtazapine and Completed suicide – a phase IV clinical study of FDA data

Summary:Completed suicide is found among people who take Mirtazapine, especially for people who are female, 60+ old, have been taking the drug for < 1 month.
The phase IV clinical study is created by eHealthMe based on reports of 51,535 people who have side effects when taking Mirtazapine from the FDA, and is updated regularly.

On Nov, 26, 2020
51,535 people reported to have side effects when taking Mirtazapine.
Among them, 1,922 people (3.73%) have Completed suicide.

Time on Mirtazapine when people have Completed suicide *:

  • < 1 month: 67.71 %
  • 1 – 6 months: 16.67 %
  • 6 – 12 months: 1.56 %
  • 1 – 2 years: 6.25 %
  • 2 – 5 years: 4.69 %
  • 5 – 10 years: 1.04 %
  • 10+ years: 2.08 %

Zopiclone and Mirtazapine drug interactions – a phase IV clinical study of FDA data

Summary: Drug interactions are reported among people who take Zopiclone and Mirtazapine. The phase IV clinical study is created by eHealthMe based on reports of 2,024 people who take Zopiclone and Mirtazapine from the FDA, and is updated regularly.

In age 30-39:

  1. Vomiting
  2. Suicidal ideation
  3. Completed suicide (act of taking one’s own life)
  4. Electrocardiogram qt prolonged
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Disorientation (disability in which the senses of time, direction, and recognition of people and places)
  7. Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
  8. Hypersensitivity
  9. Tinnitus (a ringing in the ears)
  10. Death
  11. Nausea (feeling of having an urge to vomit)
  12. Coma (state of unconsciousness lasting more than six hours)
  13. Pain
  14. Abdominal pain
  15. Akathisia (a movement disorder characterized by a feeling of inner restlessness)